The Preconditioning Phenomenon
نویسندگان
چکیده
منابع مشابه
Ischemic Preconditioning in Isolated Cells The Preconditioning Phenomenon: A Tool for the Scientist or a Clinical Reality? The Late Phase of Ischemic Preconditioning Myocardial KATP Channels in Preconditioning
The possibility that an innate mechanism of myocardial protection might be inducible in the human heart has generated considerable excitement and enthusiastic research. The potential to enhance myocardial resistance to ischemic injury in patients suffering the consequences of coronary artery disease has led to studies with more direct clinical relevance. However, in common with many other areas...
متن کاملIschemic Preconditioning in Isolated Cells The Preconditioning Phenomenon: A Tool for the Scientist or a Clinical Reality? Myocardial KATP Channels in Preconditioning The Late Phase of Preconditioning
Unlike the early phase of preconditioning (PC), which lasts 2 to 3 hours and protects against infarction but not against stunning, the late phase of PC lasts 3 to 4 days and protects against both infarction and stunning, suggesting that it may have greater clinical relevance. It is now clear that late PC is a polygenic phenomenon that requires the simultaneous activation of multiple stress-resp...
متن کاملWarm up phenomenon and preconditioning in clinical practice.
The warm up phenomenon, first described more that 50 years ago in patients with effort angina, refers to the improved performance exhibited by more than half of all patients with coronary artery disease following their first exercise test. There are several potential causes of the warm up phenomenon including: (1) an improvement in oxygen supply, which, in turn, may be caused by stenosis dilati...
متن کاملIschemic Preconditioning in Isolated Cells Second Window of Preconditioning Clinical Role for the Preconditioning Phenomenon: An Appeal for a Reasoned Approach Myocardial KATP Channels in Preconditioning
Ischemic preconditioning describes the increased resistance to myocardial infarction that follows short sublethal periods of ischemia. After the ischemia that triggers preconditioning, there are 2 phases of protection: an early (short-lived) phase termed early or classic preconditioning1 and a late (more prolonged) phase termed late preconditioning or the second window of protection.2 The purpo...
متن کاملThe preconditioning phenomenon: A tool for the scientist or a clinical reality?
The possibility that an innate mechanism of myocardial protection might be inducible in the human heart has generated considerable excitement and enthusiastic research. The potential to enhance myocardial resistance to ischemic injury in patients suffering the consequences of coronary artery disease has led to studies with more direct clinical relevance. However, in common with many other areas...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2000
ISSN: 0009-7330,1524-4571
DOI: 10.1161/01.res.87.7.543